Metabolic · Research kit
Retatrutide
4.9· 8 reviews
Triple incretin/glucagon receptor agonist for advanced metabolic and energy-balance research.
- Class
- Triple GIP/GLP-1/Glucagon agonist
- Half-life
- ~6 days
- Kit
- 10 vials
- Use
- Research only
Kit of 10 vials · 60mg per vial
Best value€949.00
€94.90 per vial · ≈ €0.13/day for ~720 days · €1.58/mg
Sold as 10-vial kits · minimum order
We don't sell single vials. Every order is a sealed 10-vial research kit — it's how serious labs and long-protocol researchers actually buy, and it's how we keep quality and price honest.
- ✓ Lower €/mg — batching 10 vials cuts our fill cost, and we pass it to you (per-vial price is 40–60% lower than typical single-vial pricing).
- ✓ One batch, one COA — all 10 vials come from the same HPLC-verified lot, so your data stays consistent across a full study.
- ✓ Real supply for real protocols — a 10-vial kit covers ~30–90 days of research depending on dose, so you're not re-ordering mid-study.
- ✓ One shipment, one customs pass — fewer parcels = lower risk, lower shipping cost per vial, faster to your bench.
Choose strength · 10 vials per kit
Bulk kit pricing
- 2+ kitssave 5%
- 3+ kitssave 10%
- 5+ kitssave 15%
Auto-applied at checkout. Stack sizes across the cart.
- HPLC ≥99%COA per batch
- Ships in 24hTracked, discreet
- Free re-shipIf lost or seized
Rilz26 at checkout — free 6-month support + 30 peptide guides
Secure bank-transfer checkout · IBAN provided instantly · Ships from Spain within 24h
€ Price per mg — honest breakdown
Every Retatrutide kit ships as 10 vials. Here's the exact maths so you can see which strength gives you the most peptide per euro. Larger kits are usually significantly cheaper per mg.
Kit price
€949.00
60 mg × 10 vials
Per vial
€94.90
€949.00 ÷ 10 vials
Total mg in kit
600 mg
60 mg × 10
Per mg
€1.58
€949.00 ÷ 600 mg
Compare every kit
| Kit | Kit price | Per vial | Per mg |
|---|---|---|---|
| 5 mg / vial | €519.00 | €51.90 | €10.38 |
| 10 mg / vial | €569.00 | €56.90 | €5.69 |
| 15 mg / vial | €639.00 | €63.90 | €4.26 |
| 20 mg / vial | €669.00 | €66.90 | €3.35 |
| 30 mg / vial | €739.00 | €73.90 | €2.46 |
| 50 mg / vial | €879.00 | €87.90 | €1.76 |
| 60 mg / vialBest €/mg | €949.00 | €94.90 | €1.58 |
What is Retatrutide?
Retatrutide is an investigational triple agonist of GIP, GLP-1 and glucagon receptors. Glucagon receptor co-activation is hypothesized to amplify hepatic lipid oxidation and energy expenditure in research models beyond what dual incretin agonists achieve.
Mechanism of action
Simultaneous activation of three incretin/glucagon receptors.
Primary research areas
Adipose biology, mitochondrial activity, energy balance.
Research notes
- Glucagon arm contributes to hepatic lipid oxidation endpoints in published preclinical work.
- Often examined alongside tirzepatide and semaglutide in comparative receptor pharmacology studies.
Retatrutide: expanded research context
Retatrutide (LY3437943) is a single-molecule triple agonist targeting the GLP-1, GIP and glucagon receptors. Its glucagon activity distinguishes it from dual-agonists like tirzepatide: alongside appetite and insulin effects, glucagon receptor stimulation is thought to increase energy expenditure and drive additional hepatic lipid mobilisation. In published Phase 2 obesity work, retatrutide produced the largest mean weight reductions yet reported for a peptide in this class.
In laboratory reference use, retatrutide is typically reconstituted in bacteriostatic water and stored refrigerated. Half-life is approximately six days, supporting once-weekly dosing schedules in study protocols. Research interest spans obesity, MASH/MASLD (hepatic steatosis), type-2 diabetes and cardiometabolic remodelling. All Regena Peptides material is supplied as a lyophilised research compound with HPLC and mass-spectrometry verification.
Published clinical evidence
Selected peer-reviewed studies and outcome trials referenced in the Retatrutide literature. Sources listed for orientation; full papers via PubMed / journal DOI.
Retatrutide Phase 2 obesity trial (48 weeks)
New England Journal of Medicine · 2023
Adults with obesity randomised to retatrutide up to 12 mg weekly showed mean weight reductions of ~24% at 48 weeks — the largest reported for a peptide agonist to date.
Retatrutide Phase 2 type-2 diabetes trial
The Lancet · 2023
In adults with T2D, retatrutide produced dose-dependent HbA1c reductions and body-weight loss superior to dulaglutide comparator at 36 weeks.
Retatrutide MASLD sub-study
The Lancet · 2024
In adults with MASLD, retatrutide reduced liver fat content by up to 82% at 24 weeks with parallel improvements in ALT and metabolic markers.
TRIUMPH Phase 3 programme (ongoing)
Eli Lilly registered protocols · 2023–2026
Pivotal outcomes programme for retatrutide across obesity, T2D, MASH, OSA and cardiovascular endpoints. Multiple readouts expected through 2026.
Verified test batches — download COAs
Independent third-party Certificates of Analysis for recent Retatrutide batches. Click any COA to open or download the full lab report — verify each result at www.janoshik.com/verify.
Verify any COA at www.janoshik.com/verify using the unique key printed on the report.
Why researchers buy from Regena
HPLC ≥99% purity
Every batch independently tested. Mass spectrometry verification on every research compound. COAs on request.
10-vial kits, properly sealed
Lyophilized peptide, rubber-stoppered amber vials, batch-coded. Stable for shipping; cold storage on arrival.
Ships from Spain, EU-wide
Tracked delivery 2–5 working days across the EU. Discreet, plain packaging. UK & worldwide options.
Secure SEPA bank transfer
Encrypted checkout, verified IBAN. No card details stored. Card payment links available on request.
How ordering works
- 1
Pick your Retatrutide kit above
Each kit contains 10 vials. Choose your strength — bigger vials give you a lower €/mg.
- 2
Secure checkout in under 2 minutes
Add to cart, fill in shipping, get your IBAN and order reference instantly.
- 3
Pay by bank transfer (or card on request)
Bank transfer is fastest and fee-free. Need a card? Message us on WhatsApp and we'll send a payment link.
- 4
We ship within 24 hours
You get a tracking number by email + WhatsApp. EU delivery 2–5 working days. COA included on request.
Frequently asked questions
Research-use disclaimer
Information on this page is provided for educational and scientific reference purposes only. Retatrutide is a research compound intended for in-vitro laboratory investigation by qualified professionals. Nothing here constitutes medical advice, dosing guidance or a recommendation for human or veterinary use. Half-life and mechanism descriptions reflect published literature approximations.
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Free download · PDF
Free: Peptide Storage & Reconstitution Guide
30-page PDF — vial handling, sterile reconstitution, dosing math, cold-chain storage. Plus a daily research insight email from the lab.
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Affiliate program · 20% commission
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Apply to become an affiliateRetatrutide — shipped to research hubs worldwide
Same HPLC-verified Retatrutide batch, same COA — tracked delivery to laboratories and independent researchers across Europe, the UK, the USA and beyond. Pick a hub for local shipping window and currency notes.
- Retatrutide for Stoke-on-Trent researchers
- Retatrutide for Tarragona researchers
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Customer reviews
What researchers say about Retatrutide
- Verified
COA matched batch number exactly
Ordered three batches of BPC-157 over four months. Each shipment arrived cold-packed with a COA and the batch numbers cross-checked against the public testing database. Purity reported between 98.7% and 99.2% — consistent with what we measured in-house by HPLC.
Dr. M. AnderssonStockholm, Sweden - Verified
Fast UK delivery, clean reconstitution
Discreet packaging, arrived in 48 hours to London. Lyophilised cake was firm, dissolved completely in bac water with no cloudiness. Dose math in IU on the calculator made repeat dosing trivial.
J. WhitmoreLondon, UK - Verified
Best documentation I've seen from a supplier
We compared three suppliers as part of a sourcing audit. Regena was the only one with chromatograms, retention times and lab-named COAs published per batch. That's the standard the rest of the industry should meet.
Prof. L. RomanoMilan, Italy - Verified
Good product, customs took an extra day
Product itself is excellent — clean reconstitution, COA available. Customs added 24 hours which is outside Regena's control. Support replied within an hour when I asked for an update.
K. PetersenCopenhagen, Denmark - Verified
Independent lab agreed with stated purity
We sent a sub-sample to an independent lab. Their result was within 0.4% of the published Regena COA. That's a level of transparency you almost never see in research-peptide sourcing.
Dr. S. PatelBirmingham, UK - Verified
Cold chain held the whole way
Temperature indicator strip in the package stayed in the green. Vials still chilled on arrival despite a 3-day route. Whoever packs these boxes knows what they're doing.
A. MüllerBerlin, Germany
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Cite this reference
Researching Retatrutide?
Copy a ready-made citation or HTML link. Backlinks from research blogs, lab wikis and biohacker communities help others find verified peptide sources.
Regena Peptides. (2026-07-18). Retatrutide — HPLC-verified research peptide. https://www.regena-peptides.com/peptides/retatrutide
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