Tripeptide research compound

Buy KPV — α-MSH Tripeptide Research Compound (HPLC-Verified)

KPV (Lysine-Proline-Valine) is the C-terminal tripeptide fragment of α-MSH, studied in laboratory research models for its modulatory effects on inflammatory signalling pathways. This guide covers what KPV is, how Regena Peptides verifies every batch, and how to source vials reliably across Spain, the UK, mainland Europe and the USA.

What KPV is and why it's studied

KPV is the three-residue C-terminal sequence of α-melanocyte-stimulating hormone (α-MSH). The full α-MSH peptide carries broad neuro-hormonal activity, but the KPV fragment retains the immunomodulatory tail without engaging melanocortin receptors that drive pigmentation. Published preclinical research has explored KPV in inflammatory bowel models, dermatological inflammation panels and mucosal-immunity assays.

Its short sequence makes KPV inexpensive to synthesise and easy to dissolve, but the same short sequence means batch identity is best confirmed by mass spectrometry rather than HPLC alone — the molecule's small size means impurity peaks can co-elute on standard reverse-phase gradients.

How Regena verifies every KPV batch

Each KPV batch is independently tested before release. The COA reports HPLC main-peak purity (target ≥99.0%), mass-spectrometry confirmation of the calculated molecular weight, peptide content, and residual moisture. Mass spec is doubly important on short peptides because impurity peaks can hide under the main HPLC band.

Janoshik Analytical is the default verification partner. Per-batch reports are published on the lab reports page and traceable to the batch number printed on every vial cap.

Storage, reconstitution and handling

Lyophilised KPV is supplied as a sterile white powder under inert atmosphere. Hold unopened vials at 2–8 °C and transfer to −20 °C only if reconstitution will not happen within 8–12 weeks. Reconstitute with bacteriostatic water for a 28-day in-use stability window under refrigeration; sterile water is acceptable for same-day work but not for multi-day storage.

KPV dissolves readily — solutions should be clear and colourless within seconds of gentle swirling. Cloudy reconstitution is the most common warning sign of handling error or undisclosed impurities. Most laboratories store working solutions at 1–5 mg/ml in single-use aliquots.

Buying KPV in Spain and across Europe

Regena dispatches KPV from the Costa del Sol with same- or next-day Andalucía delivery and 24–48 hour Spain-wide tracked courier coverage. Cross-border EU shipping uses DHL Express with full track-and-trace to Germany, France, Italy, Portugal, the Netherlands, Belgium and Scandinavia.

Every EU shipment carries the matching batch COA and a research-use customs declaration. The consultations team will confirm import status for less common destinations before order placement.

Buying KPV in the UK

UK research clients receive KPV via tracked dispatch from the European hub in 2–4 working days. DHL Express upgrades are available for tighter timelines, and VAT and customs handling are quoted transparently at checkout.

Every UK order ships with the same independent Janoshik COA used for EU clients. Additional documentation (MSDS, CoO, CoC) is supplied on request before dispatch.

Buying KPV in the United States

US-based research clients receive KPV via discreet international dispatch in temperature-buffered packaging. Tracking is end-to-end and the COA supplied matches the EU document.

US buyers should confirm institutional research-purchasing policy before ordering. KPV is supplied strictly for research use only and not for human consumption.

KPV vs BPC-157 in inflammation research panels

Researchers building inflammation-focused panels often include both KPV and BPC-157. The two molecules sit in distinct mechanistic lanes — KPV operates through the α-MSH immunomodulatory tail while BPC-157 is a 15-residue fragment of a gastric protective protein with a separate set of regenerative endpoints in preclinical work.

Stocking both from the same supplier keeps COA formatting, packaging and reconstitution protocols consistent across the panel and simplifies cross-experiment troubleshooting.

Quality signals to demand from a KPV supplier

An honest KPV supplier publishes the per-batch third-party COA, names the testing laboratory, includes both HPLC and mass-spec data, and prints the batch number on the vial. Mass spec is non-negotiable on tripeptides — purity numbers from HPLC alone are not enough to confirm identity on a molecule this small.

Regena's consultations team can walk new buyers through the COA, the reconstitution maths and the storage plan before any order ships.

Frequently asked questions

What is KPV?+

KPV is the C-terminal tripeptide fragment of α-MSH (Lys-Pro-Val), studied for its immunomodulatory effects in laboratory inflammation models.

Is KPV safe for human use?+

Regena KPV is supplied strictly for in-vitro and preclinical research. It is not approved for human consumption in any jurisdiction.

What HPLC purity should I expect?+

≥99.0% main peak with mandatory mass-spectrometry identity confirmation on the per-batch COA.

How is KPV reconstituted?+

With bacteriostatic water for a 28-day in-use stability window. KPV dissolves readily — solutions should be clear and colourless.

Do you ship KPV to Spain?+

Yes, with same- or next-day Andalucía delivery and 24–48 hour Spain-wide tracked dispatch.

Do you ship KPV to the UK?+

Yes — 2–4 day tracked dispatch from the European hub with VAT and import handling included.

Do you ship KPV to the USA?+

Yes, with discreet tracked international dispatch in temperature-buffered packaging.

How is KPV different from BPC-157?+

KPV is a three-residue α-MSH C-terminal fragment; BPC-157 is a 15-residue gastric protein fragment. Different mechanisms, different research lanes.

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