Peptide education, written for scientists

What Are Research Peptides?

A plain-English primer on research peptides: what they are, how they differ from clinical-grade compounds, and how scientists actually use them.

What Is Research Grade?

What 'research grade' actually means, the minimum purity bar to expect, and how to tell a real research-grade supplier from a marketing one.

Understanding Certificates of Analysis (COAs)

How to read a peptide COA: purity by HPLC, identity by mass spec, batch codes, retention time and the signature block.

Peptide Storage Guide

How to store lyophilised and reconstituted research peptides to preserve potency: temperature, light, moisture and time windows.

Understanding Purity Testing

Why HPLC + mass spectrometry is the gold standard for verifying research peptide purity and identity.

Peptide Reconstitution Guide

Step-by-step procedure for reconstituting lyophilised research peptides with bacteriostatic water, including dose-per-unit math.

Understanding HPLC Testing

How HPLC quantifies peptide purity: column chemistry, gradient methods, detection wavelengths, and how to read the resulting chromatogram.

Peptide Stability

What degrades a peptide over time — oxidation, hydrolysis, aggregation — and how storage choices push the stability curve.

Proper Storage Procedures

Lab procedures for receiving, logging, storing and tracking research peptide inventory at 2–8°C and -20°C.

Laboratory Handling Techniques

Best practices for pipetting, aliquoting, weighing and dispensing research peptides without compromising integrity.

Mass Spectrometry Explained

ESI-MS and MALDI-TOF for peptide identity confirmation: ionisation, m/z, charge states and how to interpret the spectrum on your COA.

Chromatogram Interpretation

How to read peptide HPLC chromatograms: main peak, shoulders, baseline noise, deletion sequences and oxidation byproducts.

Peptide Purity Analysis

End-to-end purity analysis workflow: sample prep, method selection, calibration, integration, and reporting.

Research Methodologies

Choosing the right in-vitro model for peptide research: receptor binding, cell viability, signalling assays and stability studies.

Laboratory Testing Standards

Pharmacopoeial and ISO references for peptide testing: USP <1503>, Ph. Eur. peptide monographs, ISO 17025-aligned analytical practice.