Buy SS-31 (Elamipretide) — Cardiolipin Research Peptide

SS-31 (D-Arg-Dmt-Lys-Phe-NH2) is a synthetic tetrapeptide engineered to accumulate selectively at the inner mitochondrial membrane, where it binds cardiolipin and stabilises supercomplex assembly. Published preclinical work has explored SS-31 in cardiac ischaemia–reperfusion models, age-related mitochondrial dysfunction panels, and renal and skeletal-muscle bioenergetic studies.

Because the peptide carries a Dmt (dimethyl-tyrosine) residue and a D-arginine, SS-31 is significantly more synthetically demanding than standard L-amino-acid peptides — which is why batch testing and supplier selection matter even more than usual.

Each SS-31 production lot is independently tested before release. The COA reports HPLC main-peak purity (target ≥99.0%), mass-spectrometry confirmation of the calculated molecular weight including the Dmt and D-arginine modifications, peptide content and residual moisture.

Janoshik Analytical is the default verification partner for SS-31, with secondary verification on selected batches through additional European laboratories. Per-batch reports are published on the lab reports page and tied to the batch number printed on every vial cap.

Lyophilised SS-31 is supplied as a sterile white powder under inert atmosphere. Hold unopened vials at 2–8 °C; transfer to −20 °C if reconstitution will not happen within 8–12 weeks. Reconstitute with bacteriostatic water for a 28-day in-use stability window under refrigeration; protect from prolonged light exposure to preserve the Dmt residue.

Most laboratories work at 1–5 mg/ml stock concentrations. SS-31 is sensitive to repeat freeze–thaw cycles — aliquot the full reconstituted volume before any freeze to preserve potency across multi-week protocols.

Regena dispatches SS-31 from the Costa del Sol with same- or next-day Andalucía delivery and 24–48 hour Spain-wide tracked coverage. EU cross-border shipping uses DHL Express to Germany, France, Italy, Portugal, the Netherlands, Belgium and the Nordics.

Every EU shipment includes the matching batch COA and a research-use customs declaration. The consultations team confirms import status for less common destinations before order placement.

UK research clients receive SS-31 via tracked dispatch from the European hub, typically arriving in 2–4 working days. DHL Express upgrades are available, and VAT and customs handling are quoted transparently at checkout — no surprise charges on delivery.

All UK orders ship with the same independent Janoshik COA used for EU clients. Additional documentation is supplied on request before dispatch.

US-based research clients receive SS-31 via discreet international dispatch in temperature-buffered packaging, with end-to-end tracking. The COA supplied with each shipment is identical to the document EU laboratories receive.

US buyers should confirm institutional research-purchasing policy before ordering. SS-31 is supplied strictly for research use and is not approved for human consumption.

SS-31 and MOTS-c are often studied side-by-side in mitochondrial-bioenergetics panels, but they operate via completely distinct mechanisms. SS-31 binds cardiolipin at the inner mitochondrial membrane, stabilising electron-transport-chain supercomplex assembly. MOTS-c is encoded inside mitochondrial DNA and acts through AMPK-linked metabolic signalling.

Stocking both compounds from the same supplier keeps documentation and packaging consistent across a comparative bioenergetics panel.

SS-31 contains a Dmt residue and a D-arginine, both of which are easy to substitute with cheaper L-tyrosine and L-arginine analogues by a careless or dishonest supplier. Mass-spec identity confirmation on every batch is non-negotiable — HPLC alone cannot detect that kind of substitution.

An honest SS-31 supplier publishes the per-batch COA, names the testing laboratory, and prints the batch number on the vial. Regena's consultations team will walk a new buyer through the COA and the reconstitution plan before any order ships.