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Regenerative · Cosmetic only

GHK-Cu

4.9· 8 reviews
GHK-Cu — 1 vial · 1 g cosmetic-grade powder, Regena Peptides
1 vial · 1 g · cosmetic only
4.9 / 5

Copper-binding tripeptide widely studied in skin and hair biology.

Class
Copper-binding tripeptide
Half-life
Short (minutes systemic)
Format
1 vial · 1 g
Use
Cosmetic only

1 vial · 1 g · cosmetic only

€229.00

Mix with hyaluronic acid serum · apply topically

Quantity
1
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  • HPLC ≥99%COA per batch
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Free tracked EU shipping on orders over €300. Discreet packaging. Ships from Spain within 24h.
Every batch HPLC + mass-spec tested. COA available on request — view the COA library.
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What is GHK-Cu?

GHK-Cu is a naturally occurring copper-binding tripeptide that acts as a copper(II) chaperone, modulating ECM remodelling, antioxidant defence genes and dermal fibroblast activity.

Mechanism of action

Copper chaperone modulating ECM and antioxidant gene expression.

Primary research areas

Skin remodeling, hair follicle biology, wound studies.

Research notes

  • Sold as 1 vial of 1 g cosmetic-grade GHK-Cu powder for €229.
  • Mix with a hyaluronic acid serum and apply topically — cosmetic use only.
  • Frequently cited in cosmetic-science and wound-healing literature.

GHK-Cu: expanded research context

GHK-Cu is a naturally occurring tripeptide-copper complex (glycyl-L-histidyl-L-lysine bound to Cu²⁺). Endogenous plasma levels decline substantially with age. Its most robust published effects are on dermal fibroblast activity, wound-healing gene expression and antioxidant capacity — properties that have made it a mainstay of clinical-grade cosmetic formulation for over two decades.

Regena Peptides lists GHK-Cu in two distinct formats. The cosmetic-grade 1 g vial (this page's default) is a raw ingredient for topical formulation with hyaluronic acid serums. A separate injectable-format research kit is available under GHK-Cu (Peptide) for laboratory protocols that require sterile 10-vial packaging.

Published clinical evidence

Selected peer-reviewed studies and outcome trials referenced in the GHK-Cu literature. Sources listed for orientation; full papers via PubMed / journal DOI.

  • GHK-Cu resets gene expression toward a younger profile

    BioMed Research International · 2012 (Pickart et al.)

    Genome-wide microarray analysis found GHK-Cu modulated over 4,000 genes in human fibroblasts toward younger baseline expression patterns.

  • Effects on dermal wound repair

    Journal of Investigative Dermatology · 1993

    GHK-Cu accelerated wound contraction and collagen deposition in animal wound models, with paralleled fibroblast activity in vitro.

  • Antioxidant and anti-inflammatory activity

    Oxidative Medicine and Cellular Longevity · 2018 (review)

    Synthesis of studies showing GHK-Cu suppresses ROS accumulation and inflammatory cytokine expression in skin and neural cell models.

  • Topical cosmetic-formulation performance

    International Journal of Cosmetic Science · 2015

    Human split-face studies with GHK-Cu formulations reported improvements in skin firmness, thickness and wrinkle depth versus vehicle controls.

Verified test batches — download COAs

Independent third-party Certificates of Analysis for recent GHK-Cu batches. Click any COA to open or download the full lab report — verify each result at www.janoshik.com/verify.

BatchPurityCOA

LOT#0709 · #80244

HPLC + MS · 2025-09-23

99.7%Download →

Verify any COA at www.janoshik.com/verify using the unique key printed on the report.

Why researchers buy from Regena

HPLC ≥99% purity

Every batch independently tested. Mass spectrometry verification on every research compound. COAs on request.

Single 1 g vial, sealed

Lyophilized cosmetic-grade powder in a rubber-stoppered amber vial, batch-coded. Stable for shipping; cool, dry storage on arrival.

Ships from Spain, EU-wide

Tracked delivery 2–5 working days across the EU. Discreet, plain packaging. UK & worldwide options.

Secure SEPA bank transfer

Encrypted checkout, verified IBAN. No card details stored. Card payment links available on request.

How ordering works

  1. 1

    Add GHK-Cu to your cart above

    Sold as a single 1 g cosmetic-grade vial. Mix with a hyaluronic acid serum and apply topically — cosmetic use only.

  2. 2

    Secure checkout in under 2 minutes

    Add to cart, fill in shipping, get your IBAN and order reference instantly.

  3. 3

    Pay by bank transfer (or card on request)

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  4. 4

    We ship within 24 hours

    You get a tracking number by email + WhatsApp. EU delivery 2–5 working days. COA included on request.

Frequently asked questions

Research-use disclaimer

Information on this page is provided for educational and scientific reference purposes only. GHK-Cu is a research compound intended for in-vitro laboratory investigation by qualified professionals. Nothing here constitutes medical advice, dosing guidance or a recommendation for human or veterinary use. Half-life and mechanism descriptions reflect published literature approximations.

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GHK-Cu — shipped to research hubs worldwide

Same HPLC-verified GHK-Cu batch, same COA — tracked delivery to laboratories and independent researchers across Europe, the UK, the USA and beyond. Pick a hub for local shipping window and currency notes.

View every research hub we ship to →Browse the full peptide librarySite index

Customer reviews

What researchers say about GHK-Cu

4.9· 8 reviews
  • Verified

    COA matched batch number exactly

    Ordered three batches of BPC-157 over four months. Each shipment arrived cold-packed with a COA and the batch numbers cross-checked against the public testing database. Purity reported between 98.7% and 99.2% — consistent with what we measured in-house by HPLC.

    Dr. M. AnderssonStockholm, Sweden
  • Verified

    Fast UK delivery, clean reconstitution

    Discreet packaging, arrived in 48 hours to London. Lyophilised cake was firm, dissolved completely in bac water with no cloudiness. Dose math in IU on the calculator made repeat dosing trivial.

    J. WhitmoreLondon, UK
  • Verified

    Best documentation I've seen from a supplier

    We compared three suppliers as part of a sourcing audit. Regena was the only one with chromatograms, retention times and lab-named COAs published per batch. That's the standard the rest of the industry should meet.

    Prof. L. RomanoMilan, Italy
  • Verified

    Good product, customs took an extra day

    Product itself is excellent — clean reconstitution, COA available. Customs added 24 hours which is outside Regena's control. Support replied within an hour when I asked for an update.

    K. PetersenCopenhagen, Denmark
  • Verified

    Independent lab agreed with stated purity

    We sent a sub-sample to an independent lab. Their result was within 0.4% of the published Regena COA. That's a level of transparency you almost never see in research-peptide sourcing.

    Dr. S. PatelBirmingham, UK
  • Verified

    Cold chain held the whole way

    Temperature indicator strip in the package stayed in the green. Vials still chilled on arrival despite a 3-day route. Whoever packs these boxes knows what they're doing.

    A. MüllerBerlin, Germany

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Researching GHK-Cu?

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Regena Peptides. (2026-07-18). GHK-Cu — HPLC-verified research peptide. https://www.regena-peptides.com/peptides/ghk-cu

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