What retatrutide is
Retatrutide is a 39-amino-acid synthetic peptide engineered as a balanced agonist of three receptors: GLP-1, GIP and glucagon. The added glucagon-receptor activity is the structural feature that differentiates it from tirzepatide (dual GLP-1/GIP) and semaglutide (GLP-1 only). Published phase-2 data has driven the surge in UK research interest.
Retatrutide UK supply & legality
Retatrutide is sold as a lyophilised research peptide for in-vitro and preclinical use only — it is not a UK-licensed medicine and Regena does not sell it for human consumption. UK research teams and qualified buyers can order direct from our Marbella facility with tracked, 5-14 day delivery and a research-use customs declaration included with every shipment.
How Regena verifies every batch
Each retatrutide batch is independently tested by Janoshik Analytical before any vial is released. Reverse-phase HPLC quantifies main-peak purity (target ≥99.0%), gradient mass spectrometry confirms molecular weight, and Karl Fischer reports residual moisture. The Janoshik PDF is downloadable from our lab reports page and matches the batch number printed on the vial cap.
Retatrutide dosage references (research-use)
Published phase-2 protocols escalated doses from 0.5 mg to 12 mg weekly. Research handlers typically reconstitute lyophilised retatrutide in bacteriostatic water to a 5 mg/ml or 10 mg/ml stock for easy microlitre dispensing. Always defer to your SOP and the printed COA — this page is reference material, not a dosing recommendation.
Retatrutide vs Mounjaro (tirzepatide)
Mounjaro engages two receptors (GLP-1 + GIP). Retatrutide adds glucagon-receptor activity, which research literature hypothesises increases hepatic lipid oxidation and resting energy expenditure. Phase-2 retatrutide data has shown larger effect sizes than tirzepatide phase-2 readouts, but head-to-head trial data is limited — see our full retatrutide vs Mounjaro comparison page for the side-by-side.
Storage, reconstitution and in-use stability
Hold the unopened lyophilised vial at 2–8 °C; freeze at −20 °C only if it will not be reconstituted within 8–12 weeks. Reconstitute with bacteriostatic water (0.9% benzyl alcohol) for in-use stability up to 28 days under refrigeration. Aliquot before first freeze to avoid repeat freeze–thaw cycles, which are the single biggest cause of measurable potency loss across long-acting analogues.
UK pricing & shipping
All Regena pricing is in EUR with no hidden conversion fees. UK delivery is tracked DHL Express, typically 5-14 days door-to-door, with a customs declaration matched to the COA. We do not ship to jurisdictions that prohibit research-peptide import — the consultations team will confirm before any order is placed.
Frequently asked questions
Is retatrutide legal in the UK?+
Retatrutide is not a UK-licensed medicine. It is sold as a research peptide for in-vitro / preclinical use only. Regena does not sell or ship retatrutide for human consumption, and the responsibility for compliant research use rests with the buyer.
Where can I buy retatrutide in the UK?+
Direct from Regena Peptides. Every batch ships with an independent Janoshik HPLC and mass-spec COA, tracked DHL delivery, and a research-use customs declaration. Order from this page or the Peptide Library.
How much does retatrutide cost in the UK?+
Retatrutide is priced in EUR with no UK surcharge. Current 10-vial kit pricing is published live on the Peptide Library — kit sizes range from 5 mg/vial through 20 mg/vial depending on study duration.
Retatrutide vs Mounjaro — what's the difference?+
Mounjaro (tirzepatide) is a dual GLP-1 / GIP agonist. Retatrutide adds glucagon-receptor activity as a third mechanism. Phase-2 data has shown larger effect sizes for retatrutide, but no published head-to-head trial exists yet.
Is retatrutide a peptide?+
Yes. Retatrutide is a 39-amino-acid synthetic peptide engineered as a triple receptor agonist (GLP-1, GIP, glucagon).
How long does retatrutide take to arrive in the UK?+
Tracked DHL Express to UK addresses typically arrives in 5-14 days. Every shipment includes batch COA and a research-use customs declaration.
How is retatrutide stored?+
Lyophilised vials are held at 2–8 °C. Once reconstituted with bacteriostatic water, refrigerated in-use stability is up to 28 days. Aliquot before first freeze to avoid repeat freeze–thaw cycles.
Does retatrutide cause side effects?+
Published phase-2 research literature reports the same incretin-class profile as tirzepatide and semaglutide — primarily gastrointestinal effects during dose escalation. This page is reference material and not medical advice; consult a qualified healthcare professional for clinical questions.
Continue your research
Retatrutide cornerstone guide
Full research-use reference
Retatrutide product page
Retatrutide vs Mounjaro comparison
Triple comparison: Retatrutide vs Tirzepatide vs Semaglutide
UK research clients hub
Peptide Library
Browse the full HPLC-verified catalogue
Buy in Marbella
Local delivery across Costa del Sol
Book a free consultation
20-minute call with the Regena team
Lab reports & COAs
Batch-by-batch purity certificates
Research compounds overview
Laboratory peptides guide
Storage & reconstitution guide
Peptide glossary